DNA’s Incredible Damage Response Systems

There are many compelling evidences for God’s existence, and one example is the complexity of DNA. God’s design can be clearly seen in nature, and that includes life at the molecular level.

In this video, Dr. Rob Carter does a magnificent job discussing the latest discoveries in DNA damage response (DDR), which is far more complicated than anyone ever imagined.

One thing that makes these new discoveries so fascinating is the use of AI (artificial intelligence) in revealing how “elegant,” “beautiful,” and “complicated” these DNA repair systems are. Researchers were interested in finding new trends and features within Systems Biology and Network Analysis, and what they found revealed staggering new relationships within the cell that are now mapped out.

Dr. Carter reminds us that DNA is extremely fragile and sensitive. It can be damaged by oxygen, water, radiation, and many other natural processes. It can get twisted, break, and snapped in half. Therefore, he says, constant vigilance is required to keep it from breaking down completely.

To put this in perspective, it’s estimated there are about 1 million DNA lesions accumulated in a cell per day. If that’s true, he asks, then how can life persist? The answer lies in normal cellular maintenance.

When DNA is damaged, it can sense the damage and repair itself. If there’s a knot in the DNA, the cell can cut it apart, pass it around the other strand, and splice it together. It fixes the break and coils it back up again. This happens all the time in our cells. If the DNA breaks or snaps in half, the cell can find the separated strands, bring them together, and join them up. Or the cell could use another chromosome as a template, then join the ends together. These interactions are like three dimensional keys within the cell that allow proteins to be opened, closed, cut apart, or altered for “error free DNA replication“.

AI was set loose to identify all the different interactions scientists haven’t had time to study yet, and researchers are just beginning to learn what parts within the cell interact with other parts, how they network together, their hierarchy, and what it means to the life of an organism. Surprisingly, they found 605 proteins associated with DNA damage repair systems, more than twice as many as previously known!

“Evolution doesn’t work,” says Dr. Carter. Why? Because DNA repair systems would have to be in place from the very beginning. If the first living organism couldn’t repair itself, for instance, then the DNA, the cell and the organism would die, and life would be extinct. DNA simply can’t survive long on its own.

It’s also notable that proteins have multiple functions, so, if one part of the DNA were altered, that could have deleterious effects to other regions, causing the organism’s death. This is another serious problem for evolution.

Now, to be fair to evolutionists, one of the study’s authors stated in their introduction, “To maintain the integrity of the genome throughout cell function and division, organisms have evolved a complex network of machinery known as the DNA damage response (DDR).” This is a standard evolutionary tactic and nonsense. Evolutionists simply assume evolution, ignore the hurdles, and are willing to violate their own rules. Nowhere do they explain how evolution is even capable of evolving complex machinery. Supposedly, evolution and nature aren’t intelligent entities, so why would they care or think about maintaining integrity? That sounds like something an intelligent designer- like God- would do.

If life had to evolve via mechanisms proposed by evolutionists, there wouldn’t be enough time to manufacture the DDR required for life before the organism died. Thus, these discoveries should be a deathblow to evolution, as these DNA repair systems could not evolve in a step-by-step process over millions of years. So, instead of evolution, the best explanation for life points to God’s existence, his creation, and his brilliant design as documented in the Bible.

Check out Dr. Carter’s video for more detail.

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